Jurisdiction: National Park Service
Established: 1987
Route: 2,052 miles (3,304 km)
After many years of pressure from white settlers, 16,000 Cherokee Indians from the southeastern states were moved by the U.S. Army in the late 1830s to lands west of the Mississippi River. Various detachments followed different routes west to the Oklahoma Territory. Thousands died along the way. Today, the designated trail follows two of the principal routes: a water trail (1,226 miles) along the Tennessee, Ohio, Mississippi, and Arkansas rivers; and an overland route (826 miles) from Chattanooga, Tennessee, to Tahlequah, Oklahoma.